Escitalopram Explained: A Prescriber’s Take on Lexapro’s Role in Psychiatry

Lexapro (escitalopram) is my favorite selective serotonin reuptake inhibitor (SSRI). Alongside Zoloft (sertraline), Lexapro is one of the most prescribed antidepressants due to its efficacy, tolerability, and diversity. Read also: Looking at Zoloft as a First-Line Agent in Psychiatry Lexapro has few drug interactions and a simple dosing range, making it an easy addition to

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Looking at Zoloft as a First-Line Agent in Psychiatry

In most cases, Zoloft (sertraline) is considered the go-to SSRI for adult patients. The medication is well tolerated, has a good safety profile, and robust efficacy data that supports its FDA approvals for major depressive disorder (MDD), obsessive-compulsive disorder (OCD),  panic disorder (PD), post-traumatic stress disorder (PTSD), social anxiety disorder (SAD), and premenstrual dysphoric disorder (PMDD).

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Prozac: The Antidepressant That Changed Everything

Prozac was the first selective serotonin reuptake inhibitor (SSRI) approved to treat major depressive disorder (MDD) in 1987. This began the shift away from tricyclic antidepressants and monoamine oxidase inhibitors as Prozac is just as effective with better tolerability with a more favorable side effect profile. Prozac, like all SSRIs, functions primarily by blocking SERT

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An Overview of SSRIs with a Detailed Look at Mechanism of Action

Selective serotonin reuptake inhibitors (SSRIs) are considered the gold standard in treating depression and anxiety disorders. This class of medications includes well-known medications such as Prozac (fluoxetine), Zoloft (sertraline), and Lexapro (escitalopram).  As a PMHNP who works in outpatient psychiatry, it is rare for me to see a patient who has not trialed at least

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My Complicated Relationship with Wellbutrin

It is 8:30 pm at the WV Poison Center and the evening rush is in full-force. I am preparing for a night full of overdoses and medication events to manage when the physician in the emergency department calls with a patient who, “just prior to arrival,” ingested an “unknown amount” of their own Wellbutrin XL

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A Closer Look at Latuda for Bipolar Depression

I often see patients who have trialed and failed multiple SSRIs and SNRIs, with the complaint these medications worked at first but lost efficacy over time. I will hear things such as they noticed significant improvement in their mood in the first few months, later resulting in increased anxiety and worsening depressive symptoms. Through careful

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Lamotrigine: A Powerful Mood Stabilizer and Effective Augmentation Agent for Treatment-Resistant Depression

Lamotrigine, a drug originally developed to treat epilepsy, has gained significant attention in recent years for its role in managing mood disorders, particularly as a mood stabilizer and augmentation agent in major depressive disorder (MDD). While its primary mechanism of action was initially focused on controlling seizures, ongoing research has revealed that lamotrigine possesses unique

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Pharmacodynamics: Understanding the Action of Drugs

Pharmacodynamics is a crucial field within pharmacology that investigates how drugs exert their effects on the body, particularly focusing on the biochemical and physiological mechanisms involved. It encompasses the study of drug-receptor interactions, signal transduction pathways, and the resulting physiological responses. This discipline is essential for understanding both the therapeutic effects and potential side effects

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Introductory to Pharmacokinetics

Two terms you are most likely familiar with are pharmacokinetics and pharmacodynamics. Pharmacokinetics is the study of the action of medications in the body, including the processes of absorption, distribution, metabolism, and elimination. An easy way to remember pharmacokinetics is what the body does to a medication. Pharmacodynamics is the study of the biochemical and

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Side Effects of Antipsychotics

All medications have side effects. In fact, medication side effects can be used to a clinician’s advantage when making a decision on what medication to initiate. When clinicians are being trained, they are often taught medications by class. This makes for an easy way to remember what class is used for what purpose and in

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