Toxicology

Prozac: The Antidepressant That Changed Everything

Prozac was the first selective serotonin reuptake inhibitor (SSRI) approved to treat major depressive disorder (MDD) in 1987. This began the shift away from tricyclic antidepressants and monoamine oxidase inhibitors as Prozac is just as effective with better tolerability with a more favorable side effect profile. Prozac, like all SSRIs, functions primarily by blocking SERT

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My Complicated Relationship with Wellbutrin

It is 8:30 pm at the WV Poison Center and the evening rush is in full-force. I am preparing for a night full of overdoses and medication events to manage when the physician in the emergency department calls with a patient who, “just prior to arrival,” ingested an “unknown amount” of their own Wellbutrin XL

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